NON-ONCOGENIC ACUTE VIRAL INFECTIONS DISRUPT ANTI-CANCER RESPONSES AND LEAD TO ACCELERATED CANCER-SPECIFIC HOST DEATH

Non-oncogenic Acute Viral Infections Disrupt Anti-cancer Responses and Lead to Accelerated Cancer-Specific Host Death

In light of increased cancer prevalence and cancer-specific deaths in patients with infections, we investigated whether infections alter anti-tumor immune responses.We report that acute influenza infection of the lung promotes distal melanoma growth in the dermis and leads to accelerated cancer-specific host death.Furthermore, we show that during i

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A NEW APPROACH FOR IMPROVEMENT OF THE METHODOLOGY TO IDENTIFY A TYPE OF INTERACTION OF LACTIC ACID BACTERIA IN CONSORTIUMS OF DIFFERENT STAGES OF CULTIVATION

Existing approaches for evaluation of types of interactions between individual monocultures in consortiums allow obtaining only qualitative results (synergistic, antagonistic, additive interaction) as a one eared bridles whole, without regarding to changes in the cultivation process.Therefore, the development of a new approach for the quantitative

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(Arg)9-SH2 superbinder: a novel promising anticancer therapy to melanoma by blocking phosphotyrosine signaling

Abstract Background Melanoma is a malignant tumor with high misdiagnosis rate and poor prognosis.The bio-targeted therapy is a prevailing method in the treatment of melanoma; however, the accompanying drug resistance is inevitable.SH2 superbinder, a triple-mutant Outdoor Daybed of the Src Homology 2 (SH2) domain, shows potent antitumor ability by r

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Riparian woodland encroachment following flow regulation: a comparative study of Mediterranean and Boreal streams

Water development accompanying mankind development has turned rivers into endangered ecosystems.Improving the understanding of ecological responses to river management actions is a key issue for assuring sustainable water management.However, few studies one eared bridles have been published where ecological metrics have been quantified in response

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